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Clorazepate ( Tranxene )

Clorazepate ( Tranxene )
In Canada ( - )

Clorazepate ( Tranxene ) is an antianxiety agent ( benzodiazepine ) used primarily for relief anxiety.It may also be used to treat symptoms of acute alcohol withdrawals,to help control epilepsy, irritable bowel syndrome, tension, fatigue, panic attacks and other convulsive disorders.

Strengths:

Tables:
3.75 mg, 7.5 mg, 11.25 mg

Tables ( Long-acting ):
15 mg, 22.5 mg

Dosages: Actual dosage must be determined by a physician.

Normal dosage:

If under 9 years of age, DO NOT USE.
9 to 60 years of age, 30 mg in divided doses.
Over 60 years of age, Lower dosage increased cautiously.

Oral:
Start: 15 mg daily.
Increases: As needed.
Maximum: 60 mg in 24 hours.

Problems with:

Liver Function: N/A.
Kidney Function: N/A.

Take With: Without food is best but with food if it upsets your stomach.

Full Benefits In: First day to a week.

Missed Dose(s): If within one hour take, if over an hour skip and then continue on your normal schedule. Never Take a Double Dose.

If Stop Taking: Do not stop without consulting your physician and never abruptly if you have been taking this drug for more then 3 weeks.

Warnings

Narcotics may increase the sedative effects of this drug. Do not take other sedative, benzodiazepines,or sleeping pills with this drug. The combinations could be fatal. Do not drink alcohol when taking benzodiazepines. Alcohol can lower blood pressure and decrease your breathing rate to the point of unconsciousness.

The habit-forming potential is high. It is possible to become dependent in only two weeks.This drugs should not be taken for more then four weeks on a regular basis ( Yudofsky, Hales and Ferguson ). If you have been taking this drug regularly for three or more weeks then do not stop taking this drug abruptly,this could cause psychological and physical withdrawal symptoms.

Do not take this drug if you are pregnant. Do not take this drug if planning to become pregnant. Do not take if you are breast-feeding.

Do not give this drug to anyone under the age nine. Only use drug in small doses if over sixty with very close monitoring.

Do not use if:

  • you had negative reactions to other benzodiazepines in the past.
  • you have a history of drug dependence.
  • you have had a stroke.
  • you have multiple sclerosis.
  • if you have Alzheimer's disease.
  • if you are seriously depressed or if you have other brain disorders.

Clorazepate ( Symptoms or Effects )

Common: Clumsiness / Sleepiness.

Rare: Abdominal cramps, blurred vision, dry mouth, racing heartbeat / palpitations,shaking / slurred speech, urination problems, convulsions, hallucinations, memory loss, trouble breathing, staggering / trembling, headache, or confusion.

See physician always: Abdominal cramps, blurred vision, dry mouth, racing heartbeat / palpitations, shaking / slurred speech, urination problems, convulsions, hallucinations, memory loss, trouble breathing, staggering / trembling, headache, or confusion.

See physician if severe: Clumsiness / Sleepiness.

See physician NOW: Confusion or headaches.

Stop taking and see physician NOW: Convulsions, hallucinations, memory loss, trouble breathing, or staggering / trembling.

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